Stacey L. Harper


Stacey L. Harper
Assistant Professor
Oregon State University
Nanotoxicology; Nanomaterial-biological interactions; Nanoinformatics
harpers@science.oregonstate.edu / 541-737-2791
harpers@science.oregonstate.edu


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Stacey L. Harper, Ph.D., Assistant Professor, studies how very small substances, called nanomaterials, interact with cells, tissues and systems of plants and animals. Her goal is to determine how the widely used particles in manufacturing and consumer products affect the health of living organisms.  Stacey is a Signature Researcher of the Oregon Nanoscience and Microtechnologies Institute, working under the Safer Nanomaterials and Nanomanufacturing Initiative and has a joint position between the Department of Environmental and Molecular Toxicology and the School of Chemical, Biological and Environmental Engineering at Oregon State University.   She earned her bachelor’s degree in natural sciences and mathematics from Mesa State College, CO and her master’s and doctoral degrees in biological sciences from University of Nevada Las Vegas, NV.  In her research, she uses rapid assays to evaluate the biological activity and toxic potential of novel nanomaterials.  She works closely with industry, academic and government partners to ensure that environmental and human health considerations are addressed together with the development of new nanomaterials.  As Co-Chair of the Informatics Science Group of the NanoHealth Enterprise, she has established a collaborative, multidisciplinary research program to develop a knowledgebase of Nanomaterial-Biological Interactions (NBI) at OSU (www.oregonstate.edu/nbi).   Stacey is also a representative of the ANSI-Accredited U.S. Technical Advisory Group for ISO/TC 229 which functions to formulate positions and proposals on behalf of the U.S. with response to ISO standardization activities on environmental health and safety of nanotechnologies.  

_____________________________________________________________

 

CURRICULUM VITAE JULY 2011

STACEY LYNN HARPER

27721 Hill Top Road

Alsea, Oregon 97324

USA

phone: (541)737-2791(w)

fax: (541)737-4371

harpers@science.oregonstate.edu

 

PROFESSIONAL POSITION:

Assistant Professor of Nanotoxicology

Environmental and Molecular Toxicology

Chemical, Biological and Environmental Engineering

Oregon State University

1011 ALS           

Corvallis, Oregon  97331

 

EDUCATION:

Post-doctoral            2008.             Environmental and Molecular Toxicology, Environmental Health Sciences Center,

Corvallis, Oregon 97331.

Post-doctoral            2005.              Exposure and Dose Research Branch, Environmental Protection Agency, Las Vegas, NV

89154.

Ph.D.                2003.              Biological Sciences, University of Nevada Las Vegas, Las Vegas, NV  89154.

M.S.                  1998.               Biological Sciences, University of Nevada Las Vegas, Las Vegas, NV  89154.

B.S.                   1993.              Natural Sciences and Mathematics, Mesa State College, Grand Junction, CO  81503.

 

SCIENTIFIC INTERESTS:

Novel approaches to predictive toxicology; assimilating and fusing information on nanomaterial-biological interactions to permit data mining, generate predictive knowledge and provide information to minimize toxicity; the relationships among currently disparate exposure, dose and toxicity data in animal systems (including humans) and the degree to which those relationships can accurately be extrapolated to other systems and exposure scenarios; novel tools to determine nanomaterial characteristics; biological activity and toxic potential of novel nanomaterials; comparative physiology and toxicology.

 

PROFESSIONAL EXPERIENCE:

 January 2009 – present:  Assistant Professor, Department of Environmental and Molecular

             Toxicology & School of Chemical, Biological and Environmental Engineering, Oregon State  

University, Corvallis, Oregon.

March 2007 – December 2008:  Research Associate, Department of Environmental and Molecular

 Toxicology, Oregon State University, Corvallis, Oregon.

March 2005 – February 2007:  Scientist - National Institute of Environmental Health Sciences

Fellow, Environmental Health Sciences Center, Corvallis, Oregon.

 May 2003 – February 2005:  Biologist – Environmental Protection Agency Post-Doctoral Fellow,

 National Exposure Research Laboratory, Las Vegas, Nevada.

 August 2001 – May 2003:  Research Fellow – Marjorie Barrick Research Fellowship, University

             of Nevada Las Vegas,  Las Vegas, Nevada.

 June 2001 – August 2001:  Part-time Instructor – Human Anatomy and Physiology, University

             of Nevada Las Vegas,  Las Vegas, Nevada.

 August 1996 – May 2001:  Research and Teaching Assistant/Laboratory Coordinator,    

             Department of Biological Sciences, University of Nevada Las Vegas, Las Vegas, Nevada.

Professional Offices and Service

 

PROFESSIONAL ELECTED OFFICES:

2011-12            President for the Society of Toxicology, Pacific Northwest Chapter

2010-11            Vice-President for the Society of Toxicology, Pacific Northwest Chapter

2009 -11            Vice-Chair of ASTM International Technical Committee E56 on Nanotechnology

2009-10            Vice-President Elect for the Society of Toxicology, Pacific Northwest Chapter

2007-11            Delegate of ANSI-Accredited U.S. Technical Advisory Group for ISO/TC 229

2003-04            Secretary of the Health and Safety Committee, US Environmental Protection Agency

2000-01            Graduate Student Representative for Division of Comparative Biochemistry and Physiology for the Society of Integrative and Comparative Biology

1998-99            Secretary of the Biological Association of Graduate Students, University of Nevada, Las Vegas

1997-98            President of the Biological Association of Graduate Students, University of Nevada, Las Vegas

1992-93            President of Tri-Beta National Biological Honor Society, Mesa State College

 

PROFESSIONAL SERVICE, EDITORIAL:

     Associate Editor, Encyclopedia of Toxicology, 3rd edition. Editor-in-Chief Philip (Wexler Elsevier, 2013)

     Associate Editor, Concise Encyclopedia of Toxicology. Editor-in-Chief Philip (Wexler Elsevier, 2013)           

 

PROFESSIONAL SERVICE, BOOK REVIEWS:

     Harper, S.L.  Review of Nanotoxicology: Characterization, Dosing and Health Effects.  Doody’s

             Review Service (on-line).  Available: http//www.doody.com.  (Accessed 1/07/08).

 

PROFESSIONAL SERVICE, PANELIST:

May 2011            Panelist for a workshop to support women post-docs in the STEM fields entitled “Professional Advancement for Academic Women: The Postdoctoral Perspective” hosted by the Office of Women’s Advancement and Gender Equity, OSU. 

Jan 2007           Panelist for the public webdialogue entitled ‘Consumers Talk Nano’, a collaborative event

hosted by the Project on Emerging Nanotechnologies and Consumers Union

 

PROFESSIONAL SERVICE, COMMITTEES:

2008-11            ISO/TC 229 International Task Group on Nanotechnologies and Sustainability

 

ACADEMIC SERVICE, COMMITTEES:

CBEE Faculty Status Committee (2010-2011), 1 mid-tenure review, 2 promotions to full professor

CBEE Graduate Committee (2009)

Graduate Committee Member

·       Lisa Truong, PhD Tox (F 2007-present)

·       Benjamin Place, PhD Tox (F 2009-present)

·       Dylan Stankus, MS EnvE (F 2009)

Search Committee – Faculty Hire

·       2010-2011, Green Building Engineering and Materials Search Committee, Department of Wood Science and Engineering, OSU. 

 

ACADEMIC SERVICE, REPRESENTATIVE:

Graduate College Representative

·       Jennifer Barnett, MS Forestry Engineering (F 2010-present)

 

PUBLIC SERVICE, CONFERENCE ORGANIZATION

2010                            Conference organizer: Nanoinformatics 2010

2010            Conference organizer: Annual conference for the Society of Toxicology Pacific Northwest Regional Chapter

2010            Co-Chair of Symposium on Interdisciplinary Approaches to Safe Nanotechnologies at the fall annual conference for the Materials Research Society

2008-09            Steering committee member for the Nanotechnology Health and Safety Forum;

June 8-9, 2009.

2008            Co-Chair of Informatics Science Project Group for the NanoHealth Enterprise, a public–private partnership to address critical needs for the safe development of nanoscale materials and devices.

2008            Co-Chair Signal Transduction and Gene Regulation Session at 47th Annual Meeting of the Society of Toxicology

2006            Co-Chair Developmental Toxicity in In Vivo and In Vitro Systems Session at 45th Annual Meeting of the Society of Toxicology

1999            Chair, Second Annual Biological Association of Graduate Students Research Symposium, University of Nevada Las Vegas

1998            Organized First Annual Biological Association of Graduate Students Research Symposium, University of Nevada Las Vegas

 

PUBLIC SERVICE, REVIEWER:

2011                Manuscript reviews for Environmental Science and Technology

2011                Technical reviewer for the TechConnect World 2011: includes the Nanotech, BioNanotech and 

    Microtech conferences

2010                Review panelist for the National Science Foundation, review of the Center for

    Environmental Implications of Nanotechnology, UCLA

2008-09   Technical reviewer for NSTI Nanotech2009 Conference

2008                Peer reviewer for NY&CT Sea Grant Long Island Sound Study

2008                Technical reviewer for NSTI Nanotech2008 Conference

 

PUBLIC SERVICE, OUTREACH:

2010                Public seminar on “Nanotechnology: Huge Science at a Really Small Scale”, Friends of Yachats

                 Commons Foundation, Yachats, OR

2010                NNN Nanoinformatics e-workshop presenter

2008                Partner in the Collaborative on Health and the Environment

2008                Participating in ASTM Interlaboratory Testing on NIST reference nanomaterials

2007                Presentation to Alsea Middle School on ‘Understanding how genomic information is transforming

    society’

2005                SMILE Program – GENETICS (Genes and Environment: New Education to Involve Communities)

    Team

1997-99   Presentation to Clark High School Academy of Math, Science and Applied Technology Students

1997-98   Judge at Clark County Schools Science Fair

1997-98   Scientific presentation to Clark County Elementary Schools, Las Vegas,  Nevada

1997                Research Demonstration to Science Bowl Participants, High School Students From Clark County

    School District

1997                Participation in the High School Shadowing Program for Career Day, UNLV

 

 

Teaching/Instruction/Outreach

 

TEACHING:  

2011, Spr.            ENVE456/556, Sustainable Water Resources Development (1 Lecture)

2011, Spr.            BIO 435, Genes and Chemicals in Agriculture: Value and Risk (1 Lecture)

2010, Fall            ENGR 221, Science, Engineering and Societal Impact of Nanotechnology (Lecture & Recitation; 4.7/5.0)

2010, Spr.            BIO 435, Genes and Chemicals in Agriculture: Value and Risk (1 Lecture)

2010, Spr.            EEC 499/599, Materials Science of Nanotechnology (1 Lecture)

2010, Spr.            ENVE456/556, Sustainable Water Resources Development (Lecture & Recitation; 3.8/3.9)

2009, Fall            ENGR 221, Science, Engineering and Societal Impact of Nanotechnology (Lecture & Recitation)

2009, Spr.            ENVE456/556, Sustainable Water Resources Development (1 Lecture)

2009, Spr.            BIO 435, Genes and Chemicals in Agriculture: Value and Risk (1 Lecture)

2009, Win.            ENGR 221, Science, Engineering and Societal Impact of Nanotechnology (Lecture & Recitation)

2008, Fall            TOX 360, Toxicology (Guest Lecture on Nanotechnology)

2007, Spr.            BIOE 458, Nanotechnology (1 Lecture on Nanotoxicology)

2006, Spr.            BIOE 458, Nanotechnology (1 Lecture on Nanotoxicology)

2002, Spr.            BIO 360, Invertebrate Zoology (Laboratory Instructor)

2001, Sum            BIO 224, Human Anatomy and Physiology (Lecture)

2000, Fall            BIO 320, Invertebrate Zoology (Laboratory Instructor)

2000, Sum            BIO 224, Human Anatomy and Physiology (Lecture)

2000, Spr.            BIO 224, Human Anatomy and Physiology (Laboratory Instructor)

1999, Fall            BIO 223, Human Anatomy and Physiology (Laboratory Instructor)

1999, Spr.            CHE 475, Biochemistry (1 Lecture on Protein Synthesis)

1998, Sum            BIO 224, Human Anatomy and Physiology (Laboratory Instructor)

1998, Spr.            BIO 310, Evolution (Guest Lecture on Symbiosis)

1997, Fall            BIO 223, Human Anatomy and Physiology (Laboratory Instructor)

1997, Sum            BIO 224, Human Anatomy and Physiology (Laboratory Instructor)

1997, Sum            BIO 223, Human Anatomy and Physiology (Laboratory Instructor)

1996, Fall            BIO 190, Introductory Biology (Laboratory Instructor)

1996, Spr.            BIO 190, Introductory Biology (Laboratory Instructor)

 

ADVISING/TUTORING:

2010, Fall            9 ChE undergraduates

2011, Wint.            9 ChE undergraduates

2011, Spr.            12 ChE undergraduates

1999-2001               University of Nevada Las Vegas Athletic Department Tutor

 

MENTORING:

PhD Toxicology

·       Federico Sinche (F 2010-present)

 

MS Toxicology

·       George Tuttle (Su 2010-present)

·       Joshua Robinson (F 2010-present)

 

MS Environmental Engineering

·       Cassie Vieville (Su 2010-present)

o     1rst place poster at the Society for Environmental Toxicology and Chemistry Regional Conference (2011)

Co-Mentoring

·       Mike Sreniawski (F 2010-present) MS Public Health/Minor Toxicology

 

Johnson Fellows

·       Michael Stanfill, ChE (Su 2009), “Environmental impacts of nanomaterials”

·       Kirsten Burch, ChE (Su 2010), “Prototype development of the NanoScanner”

·       Melissa Simpson, ChE (Su 2010), “Preliminary growth inhibition study using Daphnia magna to examine the toxicity of aged vs. recently manufactured metal oxide nanoparticles”

·       Lizzy Baker, ChE (Su 2011)

·       Blake Wimer, ChE (Su 2011)

 

Undergraduate researchers

·       Aaron Anderson, ChE (F 2009 – W 2011)

·       Luke Injerd, ChE (S 2010 – W 2011)

·       Tran Vo-Vu (W2011-present)

·       Joan Erwert, Pre-Pharm (S 2011)

·       Michael Stanfill, ChE (F 2009 - present)

o   URISC summer 2011 –$1800 deferred until Fall 2011

·       Perry Kanury (W2011-present)

o    HHMI research program summer 2011 - $4000

 

ChE Senior capstone students

·       Ian Davis, ChE (W 2011), “The NanoScanner: Separation of Nanoparticles in a Microchannel Device”

·       Keith Beckman, ChE (W 2011) , “The NanoScanner: Separation of Nanoparticles in a Microchannel Device”

·       Lane Gray, ChE (W 2011) , “The NanoScanner: Separation of Nanoparticles in a Microchannel Device”

 

Engineering Senior Projects

·       Misha Sahakian (co-mentoring with Karl Haapala, MIME, F 2010-S 2011), “Assessing performance of metal machining with nanofluids”

 

Honors Thesis

·       Tara Binn, ChE, (S 2011)“Enzymatic Bioprocessing of Lignocellulosic Biomass: the Impact of Process Design Variation and Genetic Manipulation Towards a Future of Affordable Biofuels”

 

Apprentices in Science and Engineering (ASE)

·       Clayton Kilmer (Su 2010, Cottage Grove High School, junior), “The uptake and trophic transfer of quantum dot nanomaterials”

·       Claire Krizan (Su 2010, Crescent Valley High School, junior), “Comparative toxicity of sunscreens with nanomaterial and non-nanomaterial active ingredients”

·       Dana Hannibal (Su 2011, Sprague High School, sophomore)

·       Kaitlyn Furnish (Su 2011, Silverton High School, junior)

 

 

 

Research/Scholarship/Leadership

 

HONORS & AWARDS:

2010            Women in SETAC Luncheon speaker, Society for Environmental Toxicology and Chemistry

2008                Science Communication Fellow for EnvironmentalHealthNews.org

2007                Best Platform Presentation, Pacific Northwest Association of Toxicologists

2004                Superior Performance Award, US Environmental Protection Agency

2001                Marjorie Barrick Research Fellowship, University of Nevada Las Vegas

2000                Biology General Scholarship, Graduate College, University of Nevada Las Vegas

2000                Outstanding Achievement in Biology Award, University of Nevada Las Vegas

1999                University of Nevada Las Vegas Alumni Association Most Outstanding Thesis

1999                Best Student Paper Award, Arizona-Nevada Academy of Sciences

1998                College of Sciences Outstanding Thesis Award, University of Nevada Las Vegas

1998                Outstanding Young Scholar in Science and Engineering, Univ. of Nevada LV

1997                Soroptamist Award, National Soroptamist Society

1997-99   University of Nevada Las Vegas Regents Award

1993                Frank G. Brookes Award for Excellence in Scientific Research, Tri-Beta National Biological Honor  

    Society

           

SUBJECT MATTER EXPERT:

2010                Subject Matter Expert for the 2010 National Nanotechnology Initiative capstone workshop

2009-11   Subject Matter Expert:  Integrative Cancer Research Nanotechnology Working Group

 

GRANTS/FUNDING:

2010                AFRL/ONAMI/Safer Nanomaterials and Nanomanufacturing Initiative, $115,000

2009                AFRL/ONAMI/Safer Nanomaterials and Nanomanufacturing Initiative, $105,000

2008                NIH/NIEHS/Nanoscience and Nanotechnology in Biology and Medicine, $1,535,979

2008                AFRL/ONAMI/Safer Nanomaterials and Nanomanufacturing Initiative, $180,000

2008                AFRL/ONAMI/Safer Nanomaterials and Nanomanufacturing Initiative, $90,000

2007                AFRL/ONAMI/Safer Nanomaterials and Nanomanufacturing Initiative, $79,650

2002                Graduate Research Training Assistantship, Graduate College of UNLV, $3000

2000                James F. Adams / GSA Scholarship, Graduate College of UNLV, $1000

2000                Graduate Research Training Assistantship, Graduate College of UNLV, $3000

2000                Summer Session Scholarship, University of Nevada Las Vegas, $2000

1999                Graduate Research Training Assistantship, Graduate College of UNLV, $3000

1997-00   Graduate Student Association Grant, University of Nevada Las Vegas, $500 (1997), $450 (1998),

    $950 (1999), $1420 (2000)

1997-98   Biological Association of Graduate Students Travel Grant, University of Nevada Las Vegas, $200

    (1997), $200 (1998), $200 (1999)

1998                Arizona-Nevada Academy of Science Research Grant-in Aid, $250

1998                Department of Biological Sciences Travel Grant, UNLV, $500

1997                Aquatic Biology Research Travel Fund, Department of Biological Sciences, University of Nevada

    Las Vegas, $425

 

 

 

CONTRACTS:

2011                Subject Matter Expert:  Integrative Cancer Research Nanotechnology Working Group, $8,000

2010                Subject Matter Expert:  Integrative Cancer Research Nanotechnology Working Group, $16,000

2010                Subject Matter Expert:  Integrative Cancer Research Nanotechnology Working Group, $12,686

2009                Subject Matter Expert:  Integrative Cancer Research Nanotechnology Working Group, $28,590

 

PEER REVIEWED PUBLICATIONS:  

     Harper, S.L., J.L. Carriere, J.M. Miller, J.E. Hutchison, B.L.S. Maddux and R.L. Tanguay.  2011.  Systematic

evaluation of nanomaterial toxicity: utility of standardized materials and rapid assays. ACS Nano 10.1021/nn200546k.   In press.

    Thomas, D.G., F. Klaessig, S.L. Harper, M. Fritts, M.D. Hoover, S. Gaheen, T.H. Stokes, R. Reznic-Zellen, E.T.

Freund, J.D. Klemm, D.S. Paik and N.A. Baker.  2011.  Informatics and standards for nanomedicine technology.  Wiley Interdisciplinary Reviews: WIREs Nanomedicine and Nanobiotechnology.  In press.

     Stone, D.L., B.J. Harper, I. Lynch, K. Dawson and S.L. Harper.  2010.  Exposure assessment: 

Recommendations for nanotechnology-based pesticides.  International Journal of Occupational and     Environmental Health 16:  467-474.

     Harper, S.L., J. Hutchison, B.L.S. Maddux and R.L. Tanguay.  2010.  Integrative strategies to understand

nanomaterial-biological interactions. International Perspectives on Environmental Nanotechnology: 

            Applications and Implications 2: 51-56.

     Harper, S.L., C.Y. Usenko, J. Hutchison, B.L.S. Maddux and R.L. Tanguay.  2008.  In vivo

             biodistribution and toxicity depends on nanomaterial composition, size, surface

             functionalization and route of exposure.  Journal of Experimental Nanoscience 3: 195-206.     

     Vercruysse, K.P., S.L. Harper, D.M. Ivory, M.M. Whalen, K.S. Saili and R.L. Tanguay.  2008. 

Potential anti-inflammatory properties of biologically-synthesized nanoparticles of gold or silver.         

Nanotech 2008 2: 501-504.

     Harper, S.L., J.A. Dahl, B.L.S. Maddux, R.L. Tanguay and J.E. Hutchison.  2008.  Proactively

            designing nanomaterials to enhance performance and minimize hazard.  International Journal

            of Nanotechnology 5: 124-142.      

     Usenko, C.Y., S.L. Harper and R.L. Tanguay.  2008.  Exposure to C60 elicits an oxidative stress

response in embryonic zebrafish.  Toxicology and Applied Pharmacology 229, 44-55.  

     Usenko, C.Y., S.L. Harper and R.L. Tanguay.  2007.  In vivo evaluation of carbon fullerene

toxicity using embryonic zebrafish.  Carbon 45: 1891-1898.    

     Harper, S.L., B.L.S. Maddux, J. Hutchison and R.L. Tanguay.  2007.  Biodistribution

and toxicity of nanomaterials in vivo:  effects of composition, size, surface functionalization 

               and route of exposure.  Nanotech 2007 2: 666-669. 

     Harper, S.L. and C.L  Reiber.  2006.  Cardiac development in crayfish: ontogeny of cardiac

             physiology and aerobic metabolism in the red swamp crayfish Procambarus clarkii.  Journal

               of Comparative Physiology B 176: 405-414.

     Harper, S.L. and C.L  Reiber.  2006.  Metabolic, respiratory and cardiovascular responses to

acute and chronic hypoxic exposure in tadpole shrimp Triops longicaudatus.  Journal of Experimental

Biology 209: 1639-1650.

     Rogers, K.R., S.L. Harper, G. Robertson.  2005.  Screening for toxic industrial chemicals using

            semipermeable membrane devices with rapid toxicity assays.  Analytica Chimica Acta 543: 

             229-235.    

     Harper, S.L. and C.L  Reiber.  2004.  Physiological development of the embryonic and larval

             crayfish heart.  Biological Bulletin 206:  78-86.

     Reiber, C.L. and S.L. Harper.  2001.  Perspectives on cardiac physiological ontogeny in

             crustaceans.  Zoology  104:  103-113.

     Harper, S.L. and C. L. Reiber.  2000.  Developmental cardiac response to GABA in the red swamp

             crayfish Procambarus clarkii and the relevance to crayfish burrow ecology.  Journal of

             Arizona-Nevada Academy of Science  32 (2):  158-163.

     Harper, S.L. and C.L  Reiber.  2000.  Ontogeny of neurohormonal regulation of the

             cardiovascular system in crayfish Procambarus clarkii.  Journal of Comparative Physiology

             B  171:  577-583.

     Harper, S.L. and C.L. Reiber.  1999.  Influence of hypoxia on cardiac functions in the grass

             shrimp (Palaemonetes pugio Holthius).  Comparative Biochemistry and Physiology A. 124: 

             569-73.

 

PUBLISHED PROCEEDINGS:

     Koretsky, M.D., A. Yokochi and S.L. Harper.  2011.  Development of an option in nanotechnology: elements

of student learning.  Proceedings of the IEEE Nano Conference, Portland (USA) August 15-19, 2011.  Accepted.

     Mishra, A., S.L. Harper and S-I. Yun.  2011.  Interaction of biosynthesized gold nanoparticles with genomic

DNA isolated from E. coli and S. aureus.  Proceedings of the IEEE Nano Conference, Portland (USA) August 15-19, 2011 Accepted.

     Harper, S.L., C. Usenko and R.L. Tanguay.  2006.  Differential distribution and toxicity of

            nanomaterials in vivo.  Proceedings of the American Institute of Chemical Engineering 

(AIChE) Annual Meeting, San Francisco (USA) November 12-17, 2006

 

BOOK CHAPTERS:

     Usenko, C.Y., S.L. Harper and R.L. Tanguay.  2010.  Fullerene C60 Toxicology.  In Handbook of

Nanophysics: Nanomedicine and Nanorobotics.  Editor Klaus D. Sattler.  (pp. 17.1-17.8)  Taylor and Francis, London, England. 

     Troung, L., S.L. Harper and R.L. Tanguay.  2009.  Evaluation of embryotoxicity using the zebrafish model. 

In Methods in Molecular Medicine.  Editor Jean-Charles Gautier.  (pp. 271-279) Humana Press,

Totowa, NJ.

 

DISSERTATION/THESIS (Chapman is former name)

     Harper, S.L.  2003.  Tadpole shrimp (Triops longicaudatus) responses to acute and developmental

             hypoxic exposure.  Dissertation.  University of Nevada Las Vegas.

     Chapman, S.L.  1998.  Developmental physiology of the red swamp crayfish Procambarus clarkii. 

             Thesis.  University of Nevada Las Vegas.     

 

ADDITIONAL PUBLICATIONS/REPORTS:

2010                Nanoinformatics 2020 Roadmap - http://www.internano.org/content/view/510/251/

2007                SNNI-ONAMI comments on the EPA’s Nanoscale Materials Stewardship Program and

    TSCA Inventory Status of Nanoscale Substances, Docket Identification Number:  EPA-HQ-OPPT-

    2004-0122

 

EDITORIALS:  

     Harper, S.L.  2008.  The Complex Task of Defining Nanomaterial-Biological Interactions.  SPIE

             Newsroom.  DOI: 10.1117/2.1200901.1427   

 

 

PUBLISHED ABSTRACTS / PRESENTED RESEARCH:       

     Sinche, F., M.R. Mackiewicz and S.L. Harper.  “Evaluating the toxicological response of peptide-based

nanochelators using the zebrafish model.  GreenerNano2011 Annual Conference.

     Viéville, C. and S.L. Harper.  “A novel approach to assess nanomaterial impacts on aquatic ecosystems:

‘nanocosms’”.  GreenerNano2011 Annual Conference    

     Harper, S.L., T. Svoboda and G. Tuttle.  “Nanocosms” a novel system to rapidly access 

environmental impacts of nanomaterial exposure on aquatic systems. 2010. Pacific

Northwest Association of Toxicologists Annual Meeting.           

     Harper, S.L. and K.E. Cleveland.  The knowledgebase of nanomaterial-biological interactions. 

GreenerNano 2010 Annual Conference.

     Truong, L., T. Zaikova, E. Richman, J. Miller, S.L. Harper, J. Hutchison and R. Tanguay.  Integrative

            strategy to develop greener nanotechnology.  GreenerNano 2010 Annual Conference. 

     Usenko, C.Y., S.L. Harper, C.W. Isaacson, J.A. Field, and R.L. Tanguay.  2009.  Evaluation of C60 toxicity: 

            effect of preparation and aqueous suspension.  30th Annual Meeting of the Society of

            Environmental Toxicology and Chemistry. 

     Harper, S.L.  2008.  The emerging role of academic institutions in standards development.    

             Nanotechnology Workshop: Enabling Standards for Nanomaterial Characterization, hosted by NIST in   

             Gaithersburg, MD.

     Harper, S.L., J.E. Hutchison, B.L.S. Maddux, and R.L. Tanguay.  2008.  Integrative strategies to     

             understand nanomaterial-biological interactions.  International Environmental Nanotechnology 

             Conference:  Applications and Implications hosted by the EPA in Chicago, IL.

     Harper, S.L., K.S. Saili, L. Troung, S. Lee and R.L. Tanguay.  2008.  Integrative research strategies to

             evaluate environmental health and safety of nanomaterials.  29th Annual Meeting of the Society of

             Environmental Toxicology and Chemistry. 

     Saili, K.S., S.L.Harper, K.P Vercruysse and R.L. Tanguay.  2008.  Gold and silver nanomaterials

             reduce the inflammatory response to injury in a larval zebrafish model.  Pacific Northwest Association    

             of Toxicologists.

     Maddux, B.L.S., Harper, S.L., Tanguay, R.L. and J.E. Hutchison.  2008. Addressing environmental,

             health and safety challenges in nanomaterials research through green nanoscience.  The 236th

             ACS National Meeting. 

     Harper, S.L. 2008.  Integrative approaches to greener nanotechnology.  North American Hazardous  

             Materials Management Association – 2008 Northwest Hazardous Waste Conference.

     Maddux, B.L.S., Harper, S.L., Tanguay, R.L. and J.E. Hutchison.  2008.  Developing proactive

             design strategies in nanoscience to reduce uncertainty and enhance performance and minimize 

             hazard.  12th Annual Green Chemistry and Engineering Conference, Environmental Decision

             Making and Metrics.

     Tanguay, R.L., Usenko, C.Y., and S.L. Harper.  2008.  In vivo nanomaterial-biological

             interactions: defining structure response relationships.  The 235th ACS National Meeting.            

     Harper, S.L., K.S. Saili, D. Rohman, L. Duong, S. Lee and R.L. Tanguay.  2008.  Comparative

             nanotoxicology:  strategies to evaluate nanomaterial-biological interactions.  PNW-SETAC

             17th Annual Meeting.

     Harper, S.L., S. Lee and R.L. Tanguay.  2008.  An EZ metric for evaluating nanomaterial-

             biological interactions.  Society of Toxicology 47th Annual Meeting.

     Tanguay, R.L., L.K. Mathew and S.L. Harper.  2008.  Unraveling environmental biological

             interactions using zebrafish.  Society of Toxicology 47th Annual Meeting.

     Park, S., B. Bermardi, Y.Wang, T. Maloney, S.L. Harper, S. Lee and R.L. Tanguay.  2008.  The

             nanomaterial-biological interactions knowledgebase.  Greener Nano 2008.

     Harper, S.L., S. Lee and R.L. Tanguay.  2007.  An integrative, comparative database system to

             consolidate, integrate and analyze data on nanoparticle-biological interactions.  MicroNano

             Breakthrough Conference 2007.

     Harper, S.L., S. Lee and R.L. Tanguay.  2007.  An integrative knowledgebase of

             nanomaterial-biological interactions.  Pacific Northwest Association of Toxicologists.

     Harper, S.L., B.L.S. Maddux, J.E. Hutchison and R.L. Tanguay.  2007.  Biodistribution and

             toxicity of nanomaterials in vivo:  effects of composition, size, surface functionalization and

             route of exposure.  NSTI Nanotech 2007.

     Harper, S.L., R.L. Tanguay and J.E. Hutchison.  2007.  In vivo toxicity evaluations of gold

             nanoparticles: proactively designing safer nanomaterials.  Society of Toxicology 46th Annual

             Meeting.

     Miller, J., Harper, S.L. and J.E. Hutchison.  2007.  In vivo toxicity evaluations of

             gold nanoparticles: proactively designing safer nanomaterials.  Safer Nano 2007.

     Harper, S.L. and R.L. Tanguay.  2007.  Development of a nanomaterials effects database using a

             mass collaborative approach.  Safer Nano 2007.

     Harper, S.L.  2006.  ONAMI’s - Safer nanomaterials and nanomanufacturing initiative: 

             Recommendations for the FDA Nanotechnology Task Force.  Public Meeting on

             Nanotechnology Materials in FDA Regulated Products, Bethesda, MD.

     Usenko, C.Y., Harper, S.L., Tanguay, R.L.  2006.  Assessment of carbon fullerene-induced

             toxicity in embryonic zebrafish. SETAC.

     Usenko, C.Y., Harper, S.L., Tanguay, R.L.  2006.  In vivo assessment of carbon fullerene-induced

             toxicity.  PANWAT.

     Harper, S.L. and R. Tanguay.  2006.  Assessing the toxic potential of acute exposure to engineered

             nanomaterials.  Society of Toxicology 45th Annual Meeting.

     Dellarco, M., R.P. Zendzian, J.B. Knaak, R. Tornero-Velez, S.L. Harper, F.W. Power and C.C.

             Dary.  2005.  Is there a structural relationship between the triazole fungicides and their

             percutaneous absorption?  Society of Toxicology. 

     Rogers, K.R., S.L. Harper and G. Robertson.  2005.  Screening for toxic industrial chemicals using

             semipermeable membrane devices interfaced with rapid toxicity assays.  Society of

             Toxicology 44th Annual Meeting. 

     Tornero-Velez, R., W. Longest, S. Harper, C. Dary, J. Blancato.  2004.  Advanced computational

             methods in dose modeling: Application of computational biophysical transport,

             computational chemistry and computational biology.  Science Forum, Washington, D.C.

     Harper, S.L.  and C.L. Reiber.  2001.  Deviants of gas exchange:  adaptations of the tadpole

             shrimp.  American Zoologist 42:  74A.

     Harper, S.L. and C.L. Reiber.  2000.  Tadpole shrimp cyst distribution in a southern Nevada

             temporary rock pool.  Bulletin of the North American Benthological Society 17(1):  204.  

     Chapman, S.L.  and C.L. Reiber.  2000.  Oxygen uptake via hindgut irrigation in the   

             tadpole shrimp Triops longicaudatus.  American Zoologist 39:  68A.

     Chapman, S.L.  and C.L. Reiber.  1999.  Tadpole shrimp Triops longicaudatus may use

             their hindgut as an accessory respiratory structure.  Journal of the Arizona-Nevada

             Academy of Science  34:  16.

     Chapman, S.L. and C.L. Reiber.  1999.  Hindgut irrigation of the tadpole shrimp: 

             accessory respiratory structure?  American Zoologist  38(5):  45A.

     Reiber, C.L. and S.L. Chapman.  1999.  Ontogeny of cardiac regulation in crustaceans.     

             Comparative Biochemistry and Physiology  124A:  S65.

     Chapman, S.L.  and C.L. Reiber.  1998.  Ontogeny of neurohormonal cardiac regulation. 

             Journal of the Arizona-Nevada Academy of Science  33:  4.

     C.L. Reiber and S.L. Chapman.  1998.  Cardiac responses in grass shrimp (Palaemonetes  pugio)

             to hypoxic conditions.  Journal of the Arizona-Nevada Academy of Science  33:  14.

     Reiber, C.L. and S.L. Chapman.  1998.  Ontogeny and plasticity of regulatory mechanisms in

             crustaceans.  Meeting proceeding:  cardiac rhythms in animals: regulation, development, and

             environmental influences.  Muroran Institute of Technology, Japan.

     Chapman, S.L. and C.L. Reiber.  1998.  Ontogeny of cardiac regulation in the crayfish. 

             American Zoologist  37(5):  142A.

     Reiber, C.L.  and S.L. Chapman.  1998.  Videomicroscopic analysis of cardiac functions

             in the grass shrimp Palaemonetes pugio.  American Zoologist  37(5):  142A.

     Chapman, S.L. and C.L. Reiber.  1997.  Physiological development of the heart in

             crayfish.  Journal of the Arizona-Nevada Academy of Sciences  32:14.

 

LEADERSHIP:

1999-00   Developed a Graduate Professional Development Series for the College of Sciences at University of

    Nevada Las Vegas, series later adopted by UNLV Graduate College

 

INVITED PRESENTATIONS:

2011            “nano-TAB: specification to facilitate data exchange among nanotechnology resources” - caBIG® Architecture Workspace – presentation given 6 times during April/May

2010            “Integrative strategies to forecast the environmental fate and impact of nanomaterials” – SETAC North America

2010            “Data integration to evaluate nanomaterial-biological interactions” – National Nanomanufacturing

  Network Nanoinformatics, e-workshop

2010            “Risk Characterization Information” – National Nanotechnology Initiative Workshop, DC

2010            “Nanobioinformatics: Data Integration Strategies that Support Innovation and Governance” – GN10,

  Portland

2010            “Nanomaterial-Biological Interactions Knowledgebase” – Integrative Cancer Research Nanotechnology

  Working Group, DC

2010            “Nanotoxicology – A Rapidly Emerging Discipline” – Materials Science of Nanotechnology, OSU

2010            “New Hazards in the Workplace: Nanotechnology” – Public Health, OSU

2009            “Nanotechnology and Toxicology” – Agricultural Sciences and Forestry, OSU

2009            “Nanotechnology: Applications and Implications” – Department of Wood Science and Engineering,

  OSU.

2008            “Integrative Approaches to Greener Nanotechnologies” - Northwest Hazardous Materials Conference

  for Household and Small Business Programs, NAHMMA

2008            “Data Integration to Support the Development of Environmentally-Benign Nanomaterials” – iNANO,

  Denmark

2007              Continuing education course on the “Impacts of Nanotechnology: Nanopesticides and Environmental

  Governance” for the National Pesticide Information Center

2007            “Data Integration Strategies to Define Nanomaterial-Biological Interactions” – Intel

2007            “An Integrative, Comparative Database System to Consolidate, Integrate and Analyze Data on

  Nanoparticle-Biological Interactions” - Micro Nano Breakthrough Conference, Nanotechnology

  Environmental Health and Safety, ONAMI

2006/            “Nanotoxicology: Biological Interactions with Nanomaterials” – Department of Chemical

2007            Engineering, OSU

2006            “Biodistribution and Toxic Potential of FluoSpheresÒ and Quantum DotsÒ” - EHS Fair,

  Invitrogen/Molecular Probes

2006            “Biological Interactions with Nanomaterials” – Center for Healthy Aging and Micro Nanotechnologies

  Breakthrough Institute, OSU

 

SCIENTIFIC MEETINGS ATTENDED:

2011            Nanomaterial Registry Advisory Board Meeting (RTP)

2010            National Nanotechnology Initiative Workshop (DC)

2010            caBIG conference (Los Angeles)

2010            GN10: Greener Nano Conference (Portland)

2010            Integrative Cancer Research Nanotechnology Working Group (DC)

2010            ASTM International Executive Committee meeting (DC)

2010            Society of Toxicology Annual Meeting and ToxExpo (Salt Lake City)

2009            ANSI/ISO TC 229 Annual Meeting (Seattle)

2009            Nanotechnology Health and Safety Forum (Seattle)

2009            Greener Nano 2009 (Eugene)

2009            Regional, State and Local Nanotechnology Workshop hosted by NNI (Oklahoma City)

2008            Society of Environmental Toxicology and Chemistry (Tampa)

2008            Environmental Health Sciences Center Directors Meeting (Philadelphia)

2008            International Nanobioinformatics Workshop (Gaithersburg)

2008            NIST Workshop on Enabling Standards for Nanotechnology (Gaithersburg)

2008            International Environmental Nanotechnology: Applications and Implications (Chicago)

2008            Pacific Northwest Society of Environmental Toxicology and Chemistry (Corvallis)

2008            Society of Toxicology Annual Meeting and ToxExpo (Seattle)

2008            Greener Nano 2008 (Corvallis)

2008            NanoHealth Enterprise Initiative Coordination Committee Meeting (DC)

2007            Pacific Northwest Association of Toxicologists (Seattle)

2007            Micro Nano Breakthrough Conference (Portland)

2007            EPA Public Meeting on the Nanoscale Materials Stewardship Program (Arlington)

2007            NSTI Nanotech (Santa Clara)

2007            Society of Toxicology Annual Meeting and ToxExpo (Charlotte)

2007            Safer Nano 2007 (Eugene)

2006            American Institute of Chemical Engineering (San Francisco)

2006            Public Meeting on Nanotechnology Materials in FDA Regulated Products (Bethesda)

2006            Micro Nano Breakthrough Conference (Vancouver)

2006            Society of Toxicology Annual Meeting and ToxExpo (San Diego)

2006            1st International Symposium on Nanotoxicology, Biomedical Aspects (Miami)

2005            Genotype to Phenotype Correlation in Health and Disease (Welches)

2005            Superfund Basic Research Program Bioavailability Workshop (Elizabeth)

2004            Women’s Leadership Seminar (Denver)

2004            Mid-American Toxicology Course (Kansas City)

2004            International Conference on Biomarkers for Toxicology and Molecular Epidemiology (Atlanta)

2004            Society of Toxicology Annual Meeting and ToxExpo (Baltimore)

2003            Cambridge Healthtech Institute Predictive ADME and Toxicology (Boston)

2003            EPA Computational Toxicology Workshop (Research Triangle Park)

2002            Roundtable on Comparative Developmental Physiology (Glen Rose)

2002            Society of Integrative and Comparative Biology (Anaheim)

2000            North American Benthological Society (Keystone)

2000            Society of Integrative and Comparative Biology (Atlanta)

1999            Fifth International Congress of Comparative Physiology and Biochemistry (Calgary)

1999            Arizona-Nevada Academy of Science (Flagstaff)

1999            Society of Integrative and Comparative Biology (Denver)

1998            Society of Integrative and Comparative Biology (Boston)

1998            Arizona-Nevada Academy of Science (Phoenix)